Oral Histology

Questions	Answer
During odontoblast differentiation, where does fibronectin and decorin accumulate?	Along the distal pole of the differentiating cell
At what place does Dentin phospoprotein bond to collagen?	In a highly specific manner, DPP bonds to the e-band of the gap region of the type I collagen fibril
Role of Dentin Phospoprotein in mineralization	1. Transport of ions in to mineralization front; 2. Aggregation of collagen fibril; 3. Location of nucleation to specific region of collagen fibril; 4. Stabilization and orientation of formed collagen
Presence of matrix vesicle is limited to	mantle dentin is relatively less mineralized; collagen fiber are perpendicular to enamel; branched dentinal tubule; presence of mineralization by matrix mineralization
Chains in Type III collagen	only alpha 1 chains
The only glycosaminoglycans that is found unbound to any protein is	Hyaluronic acid
composition of glycosaminoglycans in mature pulp	60% Hyaluronic acid; 20% dermatan sulphate; 12% chondroitin sulphate and rest heparin sulphate
composition of glycosaminoglycans in developing pulp	Chondroitin sulphate is major amd hyaluronic acid minor component
function of versican	contribute to the bulk of proteoglycans and form large hydrated aggregates creating a gel
function of decorin	binds to type I collagen and helps in mineralization front